SUMICHIRAL OA series is a pioneer of chiral HPLC stationary phase using low molecular weight chiral selector.
Features
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Enables direct high quality separation of optical isomers.
Enables direct high quality separation of optical isomers by a large number of theoretical plate.
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Elution order inversion
In the SUMICHIRAL OA series, low molecular weight optically active compounds are immobilized onto the stationary phase. By immobilizing an antipode of this optically active component, the elution order of the target substance can be reversed. (Excluding OA-4800/4900/7000 series, 8000, AGP, CBH, and HSA)
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Applicable for LC-MS
SUMICHIRAL OA-2500/3000 series is applicable for LC-MS as the recommended mobile phase is methanol containing ammonium acetate.
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Supercritical Fluid Chromatography (SFC)
SUMICHIRAL OA-2000 and OA-4000 series are also available for Supercritical fluid chromatography (SFC).
Product lineup
Separation of enantiomers takes place due to the minor energy difference between the solute and the stationary phase caused by diastereomeric interactions (e.g., hydrogen bonding, charge transfer, coordinate bonding).
SUMICHIRAL column types, optically active component, separation mode and target substances are summarized in the table below.
Optical isomers separation columns (low molecular weight isomers)
Amide-type
| SUMICHIRAL | Opticall acitive components | Separation mode | Target substances | Columns for elution order inversion SUMICHIRAL OA |
|---|---|---|---|---|
| OA-2000 | (R)-Phenylglycine | Normal phese | Esters, alcohols, amides, ketones | OA-2000S |
| OA-2000I | Esters, ketones | OA-2000SI | ||
| OA-2500 | (R)-1-Naphtyl glycine | Reversed phese* | Carboxylic acids, alcohols, esters, ketones | OA-2500S |
| OA-2500I | Normal phese | Esters, alcohols, ketones | OA-2500SI |
- Reversed phese* : non-aqueous reversed phase (ammonium acetate/methanol solution)
Urea-type
| SUMICHIRAL | Opticall acitive components | Separation mode | Target substances | Columns for elution order inversion SUMICHIRAL OA |
|---|---|---|---|---|
| OA-3100 | (S)-Valine | Reversed phase* | Carboxylic acids (N-amino acid derivatives) |
OA-3100R |
| OA-3200 | (S)-tert-Leucine | OA-3200R | ||
| OA-3300 | (R)-Phenylglycine | OA-3300S | ||
| OA-4000 | (S)-Valine, (S)-NEA | Normal phese | Amines, amides, aminoalcohols, alcohols, esters, phosphamides | OA-4000R |
| OA-4100 | (S)-Valine, (R)-NEA | OA-4100R | ||
| OA-4400 | (S)-Proline, (S)-NEA | OA-4400R | ||
| OA-4500 | (S)-Proline, (R)-NEA | OA-4500R | ||
| OA-4600 | (S)-tert-Leucine, (S)-NEA |
OA-4600R | ||
| OA-4700 | (S)-tert-Leucine, (R)-NEA |
OA-4700R | ||
| OA-4800 | (S)-Indoline-2-carboxylic acid, (S)-NEA |
— | ||
| OA-4900 | (S)-Indoline-3-carboxylic acid, (R)-NEA |
— |
- Reversed phese* : non-aqueous reversed phase (ammonium acetate/methanol solution)
(S)-NEA ： (S)-1- (α-Naphtyl) ethylamine
(R)-NEA ： (R)-1- (α-Naphtyl) ethylamine
- Click here for product details, separation examples, and product list of the SUMICHIRAL OA-3000 series.
- Click here for product details, separation examples, and product list of the SUMICHIRAL OA-4000 series.
Ligand exchange-type
| SUMICHIRAL | Opticall acitive components | Separation mode | Target substances | Columns for elution order inversion SUMICHIRAL OA |
|---|---|---|---|---|
| OA-5000 | (D)-Penicillamine | Reversed phase | Amino acids, hydroxy acids, amino alcohols, amines | OA-5000L |
| OA-6000 | (L)-Tartaric acid, (R)-NEA |
OA-6000R | ||
| OA-6100 | (L)-Tartaric acid, (S)-Valine, (S)-NEA |
OA-6100R |
- (S)-NEA ： (S)-1- (α-Naphtyl) ethylamine
(R)-NEA ： (R)-1- (α-Naphtyl) ethylamine
- Click here for product details, separation examples, and product list of the SUMICHIRAL OA-5000 series.
- Click here for product details, separation examples, and product list of the SUMICHIRAL OA-6000 series.
Host-guest-type
| SUMICHIRAL | Opticall acitive components | Separation mode | Target substances |
|---|---|---|---|
| OA-7000 | β-Cyclodexitrin | Reversed phase | Flavonoid derivatives, acids, neutral compunds |
| OA-7700 | Acetyl-β-cyclodexitrin | Amines | |
| OA-8000 | Chiral pseudo-crown ether | Normal phase | Primary amines |
| Reversed phase |
- Click here for product details, separation examples, and price table of the SUMICHIRAL OA-7000 series.
- Click here for product details, separation examples, and price table of the SUMICHIRAL OA-8000 series.
Optical isomer separation columns (proteins)
| SUMICHIRAL | Opticall acitive components | Separation mode | Target substances |
|---|---|---|---|
| AGP | α1-acid glycoprotein | Reversed phase | Acids, bases, neutral compounds, amides, ketones |
| CBH | Cellobiohydrolase | Reversed phase | Bases |
| HSA | Human serum albumin | Reversed phase | Acids |
Product list
Contact Us for HPLC Columns
Please contact us for any information on related to HPLC columns.
Materials Division (Column Sales Team)
- Telephone
- +81-6-6466-5243
- FAX
- +81-6-6466-5255