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Guard Filters SUMIPAX Filter

Porous glass filter to extend the lifetime of column without changing its separation performance

SUMIPAX Filter (for analysis) is a guard column which houses a 4 mmφ × 4 mmL cylindrical glass filter with 2-μm through holes. When a sample is analyzed using HPLC, performance of separation column decreases because:

  1. substances contained in the sample are adsorbed at the column entrance, and chemically modify the surface of packing materials; and/or,
  2. minute dust generated from pump, injector, etc. accumulates in the column, and gradually modifies the column physically.

SUMIPAX Filter is a filter with guard column functions. By inserting before a column, it prevents deterioration of the column.

SUMIPAX Filter dimensions and bonded phase

SUMIPAX Filter dimensions

 

Dimensions, construction Pressure drop at flow rate in the parenthesis Internal diameter of compatible columns Flow rate range
SUMIPAX Filter
Anlytical
Length4mm
Diameter4mm
About0.1 MPa( 1mL/min)
About0.8 MPa(10mL/min)
4, 4.6, 6, 8, 10 0.2 mL/min~
10.0 mL/min
SUMIPAX Filter
Semi-micro
Length2mm
Diameter2mm
0.1MPa(0.2mL/min)
About 0.4 MPa(2mL/min)
1, 2, 3, 4,4.6, 6 0.05 mL/min~
2.0 mL/min
SUMIPAX Filter
Preparative
Fitted inside with several filters About0.1 MPa(20mL/min)
About0.6 MPa(100mL/min)
10, 20, 50 5.0 mL/min~
100 mL/min
*Mobile phase: methanol/water (1/1)

SUMIPAX Filter bonded phase

  Filter substrate Compatible columns Applicability
SUMIPAX Filter
PG-ODS
Porous glass substrate treated with ODS and then endcapped
  • ODS columns
  • Optical isomer separation columns

SUMICHIRAL OA series

  • First selection for a wide range of diverse compounds.
  • Applicable for both reversed-phase systems and normal phase systems.
SUMIPAX Filter
PG-OH
Porous glass substrate as received
  • Silica gel columns
  • Optical isomer separation columns

SUMICHIRAL AGP、CBH、HSA

  • Highly hydrophobic or highly adsorbable compounds
  • Protein-based chiral stationary phases

Application of SUMIPAX Filter

Analytical HPLC filters

Semi-micro HPLC filters

Applications of semi-micro HPLC by connecting with SUMIPAX Filter PG-ODS (for semi-micro HPLC) are shown below. No change is observed on chromatograms before and after connection. Semi-micro HPLC filters are also useful for LC-MS.

SUMIPAX Filter HB (hybrid-type)

The SUMIPAX Filter HB is line-upped for ultra high performance liquid chromatography

Features of SUMIPAX Filter HB

The dual layer structure improves the particulate capture effect of the filter
⇒ By combining porous glass and sintered metal filter, the particulate capture rate is drastically improved compared to when one of them is used uncombined.

  • Deactivation of porous glass ⇒ Glass surface is treated with ODS and endcapping
  • Maximum filter pressure ⇒ 50 MPa
  • Low cost replacement filter ⇒ Excellent running cost performance

Particulate capture effect

Silica particulates were injected into a column fitted with a filter and the change in the column pressure was observed and compared.

Filters
  1. glass filter  
  2. sintered metal filter  
  3. HB filter (hybrid-type)
HPLC conditions
  • column Filter + SUMIPAX ODS Z-CLUE 4.6×150mm
  • mobile phase 20mmol/L ammonium acetate aqueous solution/methanol (80:20)、
  • flow rate 0.8ml/min
  • samples of injection silica particulates 0.1μm、20μg/inj
Fig. 1 Column pressure versus the number of injections in case of using only a glass filter
Fig. 1 Column pressure versus the number of injections in case of using only a glass filter
Fig. 2 Column pressure versus the number of injections in case of using only a sintered metal filter 

Fig. 2 Column pressure versus the number of injections in case of using only a sintered metal filter

When only a glass filter or only a sintered metal filter is used the column pressure barely increased after over 300 injections, indicating that the silica particles added to the mobile phase were not filtered out by the glass filter or the sintered metal filter and also passed through the column. Each filter is incapable of filtering out (capturing and eliminating) 0.1-μm silica particles by itself.

HB filter (hybrid type) has much more improved particulate capturing performance through its dual layer structure with glass filter and sintered metal filter. By connecting before a column, it extends the lifetime of the column. HB filter is particularly effective in protecting ultra-high performance LC columns.

Product list

SUMIPAX Filter for analytical HPLC

Product name Product discription Product code
SUMIPAX Filter
Starter kit PG-ODS
SUSholder 1、 filters 1 GAODS001
SUMIPAX Filter
PG-ODS【Replacement filters】
Replacement filtersー 3 GAODS003
SUMIPAX Filter
Starter kitPG-OH
SUS holder 1、filters 1 GA-OH001
SUMIPAX Filter
PG-OH【Replacement filters】
Replacement filters 3 GA-OH003
SUMIPAX Holder SUS holder 1 GAACC001
Connection kit Ferrule screws 2、PEEK tube 1 GAACC002

SUMIPAX Filter for semi-micro HPLC

Product name Product discription Product code
SUMIPAX Filter
Starter kit PG-ODS
SUS holder 1、Filter 1 GMODS001
SUMIPAX Filter
PG-ODS【Replacement filters】
Replacement filters 3 GMODS003
SUMIPAX Filter
Starter kit PG-OH
SUS holder 1、Filter 1 GM-OH001
SUMIPAX Filter
PG-OH【Replacement filters】
Replacement filters 3 GM-OH003
SUMIPAX Holder SUS holder 1 GMACC001
Connection kit Ferrule screws 2、PEEK tube 1 GMACC002

SUMIPAX Filter for preparative HPLC

Product name Product discription Product code
SUMIPAX Filter
Starter kit PG-ODS
SUS holder 1、Filter 1、Teflon packing 2 GPODS001
SUMIPAX Filter
PG-ODS【Replacement filters】
Filter 1、Teflon packing 2 GPODS002
SUMIPAX Filter
Starter kit PG-OH
SUS holder 1、Filter 1、Teflon packing 2 GP-OH001
SUMIPAX Filter
PG-OH【Replacement filters】
Filter 1、Teflon packing 2 GP-OH002
SUMIPAX Holder SUS holder 1 GPACC001
Connection kit Ferrule screws 2、SUS tube 1 GPACC002

SUMIPAX Filter HB (UHPLC)

Product name Product discription Product code
SUMIPAX Filter
HB Starter kit
SUS holder 1、Filter 1 GHODS001
SUMIPAX Filter
HB【Replacement filters】
Replacement filters 3 GHODS003
SUMIPAX Holder
(UHPLC)
SUS holder 1 GUACC001

Catalog list

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