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Reagents for Assay of Human Cytochrome P450

For development of a new drug, the metabolism study is prerequisite to elucidate the pharmacodynamic, pharmacokinetic and toxicological profiles of the drug. An assay result using human liver microsomes can predict in part the in-vivo metabolism in humans. SCAS provides the tools, specific substrates of CYP isoforms, their metabolites and inhibitors.

  Price list for reagents for investigation of human P450

1.Specific substrates		 Storage condition: Refrigeration
Product name
Code No.
Package
Price (yen)
Mephenytoin
S-001
10mg
30,000
Nirvanol
S-002
10mg
30,000
Debrisoquine
S-003
10mg
30,000
S-mephenytoin
S-004
10mg
50,000
Bufuralol
S-005
10mg
50,000


2. Metabolite
Product name
Code No.
Package
Price (yen)
4’-hydroxymephenytoin
M-001
10mg
30,000
4-hydroxydebrisoquine
M-002
10mg
30,000
6-hydroxychlorozoxazone
M-003
10mg
50,000
Oxidized nifedipine
M-004
10mg
30,000
4’-hydroxynirvanol
M-005
10mg
30,000
6β-hydroxytestosterone
 M-006
 10mg
 75,000
Hydroxytolbutamide M-007
 10mg 40,000
Hydroxybufuralol M-008
 10mg 70,000
4’-hydroxydichlofenac M-009 10mg 50,000


3. Inhibitor
Product name
Code No.
Package
Price (yen)
Sulfaphenazole
I-001
10mg
10,000

The prices shown above do not include the consumption tax. (April, 2009)
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